Jobs at ICON plc

Support study start-up, site activation readiness, and maintenance tasks including ICF customization, translations, IRB/EC submissions, and eTMF documentation. Assist contract workflows and amendments, liaise with cross-functional teams, and work flexible hours to support global clinical trial operations.

Leads IT project and program management activities, including planning, scope definition, cross-functional implementation, stakeholder communication, documentation, reporting, and team mentoring. Develops project strategies, manages competing priorities, applies project management methodologies, and ensures successful delivery of IT initiatives. Requires experience leading projects in the pharmaceutical or biotech industry and willingness to travel approximately 1%.

Leads clinical data management teams and oversees delivery across clinical trial projects. Responsibilities include people management, resource planning, operational metrics, quality and compliance, audit and inspection readiness, risk management, client and sponsor engagement, process improvement, and technology adoption. The role requires extensive clinical data management experience, knowledge of GCP and regulatory requirements, and demonstrated leadership in global, matrixed environments.

Leads clinical systems teams and oversees RPA, system integration, and AI/ML projects. Ensures study goals, timelines, quality standards, client requirements, and contractual obligations are met. Provides technical support, escalation management, contingency planning, resource utilization oversight, and people leadership, including coaching, performance management, interviewing, and mentoring. Supports customer relationships and delivery teams while managing junior professionals.

Manages clinical trial site engagement and complete site management activities, from pre-trial assessment through closeout. Builds relationships with diverse stakeholders, supports regulatory presentations, ensures compliance with ICH-GCP and trial regulations, and coordinates multiple deliverables. The role requires strong organization, communication, problem-solving, and clinical research or monitoring experience, along with approximately 60% travel.

Owns end-to-end study financial analysis, including revenue forecasting, budget reconciliation, invoicing, billing opportunities, financial KPIs, and margin analysis. Prepares sponsor MIS reports, evaluates financial and operational metrics, supports management presentations, monitors contracts, and partners with project management and finance leadership. The role also contributes to process improvement and decision-making across clinical research project portfolios.

Analyzes and improves engineering systems and processes, develops and validates models, and provides data-driven recommendations. The role involves full-stack .NET development using C#, ASP.NET, Angular or React, database development, REST APIs, cloud services, source control, troubleshooting, application support, and Agile delivery. The engineer collaborates with analysts, QA teams, project teams, and stakeholders to implement scalable solutions and optimize performance.

Manage corporate tax compliance, reporting, planning, and risk activities across multiple jurisdictions. Prepare and review tax returns, provisions, reconciliations, and effective tax rate analyses; support transfer pricing, audits, tax authorities, and transaction evaluations. Monitor legislative changes, improve tax processes and controls, and mentor colleagues while collaborating with finance stakeholders and external advisors.

Lead the engineering, operation, security, and continuous improvement of enterprise endpoint and virtual desktop platforms. The role owns EUC technical decisions, major incident resolution, secure configuration baselines, change deployments, operational dashboards, compliance, and service reliability. It collaborates across infrastructure, security, service desk, and application teams, mentors junior engineers, and participates in on-call support.

Leads clinical data management activities for sponsor-dedicated studies, including data management planning, discrepancy resolution, data reconciliation, coding, cleaning, documentation, and regulatory compliance. Collaborates with clinical operations and biostatistics teams to improve data quality and meet study timelines. Mentors junior coordinators and supports study filing, archiving, and query management.

Supports HR service center activities including new-hire record setup, employment contracts, compliance screening, background checks, onboarding guidance, reporting, employee support, work allocation, and process improvement. Collaborates with HR centers of excellence, team leads, and managers to deliver accurate HR services within agreed service levels and deadlines while contributing to continual service improvement.

Lead clinical data science programming for clinical trials, designing, developing, and validating datasets, tables, listings, and figures. Collaborate with biostatisticians, data managers, and clinical teams on data specifications and analysis plans. Ensure clinical data accuracy, integrity, and regulatory compliance while mentoring junior programmers and providing technical leadership.

Support FP&A through variance analysis, forecasting, budgeting, and complex financial modeling. Prepare monthly/quarterly/annual reports, monitor financial and operational metrics, recommend process improvements, and collaborate cross-functionally to support strategic decision-making.

Lead global Study Start-Up and site activation efforts: develop and execute SSU strategy and plans, manage regulatory/ethics submissions, oversee site contracts and budgets, drive milestones to IP release, maintain CTMS/eTMF documentation, coordinate cross-functional stakeholders, mitigate risks, and report progress to sponsors and leadership.

Processes and manages investigator payments for clinical trials, ensuring accuracy, timely delivery, regulatory compliance, and proper documentation. Resolves payment discrepancies with investigators and internal teams, supports process improvements, and assists with financial reporting and analysis. The role requires finance or accounting knowledge, familiarity with clinical research payment regulations such as the Sunshine Act and FMV, Excel and financial software proficiency, and strong cross-functional communication skills.

Lead HR transformation projects by assessing HR processes, designing improvements, conducting data analysis and benchmarking, managing Workday enhancements and UAT, driving change management, and training end-users to ensure adoption of new HR processes and technologies.

Conducts financial analysis, variance analysis, forecasting, budgeting, and financial modeling to support business-unit performance and strategic decisions. Collaborates with cross-functional stakeholders to monitor financial and operational metrics, prepares periodic reports, ensures accuracy and compliance, and identifies process improvements in financial analysis and reporting.

Leads clinical data science programming for clinical trials, including designing, developing, validating, and quality-checking datasets, tables, listings, and figures. Collaborates with biostatistics, data management, and clinical teams on specifications and analysis plans. Provides technical leadership, mentors junior programmers, ensures compliance with CDISC and regulatory standards, and manages competing priorities across multiple projects.

Designs, implements, and supports customer identity solutions for B2B and B2C users using Microsoft Entra ID and Entra External ID/B2C. Integrates authentication and authorization into web and mobile applications using OIDC, OAuth2, and SAML. Supports identity federation, application onboarding, L3 troubleshooting, platform monitoring, audit readiness, compliance controls, and incident response. Collaborates with application, security, architecture, and engineering teams to deliver secure, scalable, and compliant CIAM solutions.

Develop and validate SAS, R, or Python programming solutions for clinical trial data analysis and reporting. Collaborate with data scientists and statisticians, follow regulatory and industry standards, document code and outputs, and review analysis datasets and final reports for accuracy and completeness.